Immunohistochemical Expression of Ki-67 in the Asymptomatic Fully ILTM Follicles

Authors

  • Mhd Amer Alassfar Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Damascus University, Damascus, Syria
  • Mays Imad Al-Mulla Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Damascus University, Damascus, Syria
  • Haytham Bahhah Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Damascus University, Damascus, Syria

DOI:

https://doi.org/10.30576/2414-2050.2021.07.07

Keywords:

Cell proliferation, Dental follicle, Ki-67.

Abstract

The expressions of Ki67 are the most widely used markers to show the pathological changes and early-stage tumoral alterations in vital tissues. This study aimed to Analysis the expressions of Ki67 protein in peri-coronal follicles of asymptomatic impacted lower third molars (ILTMs), thirty-seven specimens of DFs associated with impacted mandibular third molars fully covered by mucosa or bone were surgically removed from 37 patients. The patients were divided into 2 age groups. 19 of 37 DFs were between (18-24) years (Group I) and 18 were (< 24) years (Group II). Ki-67 immunostaining was evaluated in the epithelial component of the all DFs, independent-samples t-test analyses were conducted with SPSS 10.0 with statistical significance set at a P-value equal to 5%. There were statistically significant differences in the mean values of KI-67 (%) expression between (Group I) and (Group II), The values of KI-67 (%) expression in the (Group I) were smaller than in the (Group II) this study showed that DFs of elder patients have higher Ki67 expressions.

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Published

2021-03-30

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